Fat cells work different ‘shifts’ throughout the day

Fat cells in the human body have their own internal clocks and exhibit circadian rhythms affecting critical metabolic functions, new research in the journal Scientific Reports, finds.
Researchers led by Dr Jonathan Johnston from the University of Surrey conducted the first ever analysis of circadian rhythms in human fat taken from people isolated from daily environmental changes. During the study participants underwent regulated sleep-wake cycles and meal times before entering the laboratory, where they maintained this routine for a further three days. Participants then experienced a 37- hour ‘constant routine’ during which time they did not experience daily changes in light-dark, feed-fast and sleep-wake cycles. Biopsies of fat tissue were taken at six-hourly intervals and then followed by an analysis of gene expression…Read More

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